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It is no longer possible to buy Reductil from You can find out more information about Xenical here, an alternative prescription treatment for obesity.

Reductil (sibutramine) was a popular and effective medication used to aid weight loss. It was an appetite suppressant designed to combat obesity in those who have difficulties losing weight through exercise and healthy eating alone. The success rate of Reductil tablets in treating obesity was very high; however the associated adverse side effects led to the medication being withdrawn from the market in 2010.

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Why can’t I buy Reductil from anymore?

The European Medicines Agency (EMA) suspended the licence for Reductil in 2010. This means that can no longer safely prescribe the treatment and you cannot legally buy Reductil within the EU. You should be very wary if you come across a company claiming to sell or prescribe genuine Reductil online, as it is likely to be a counterfeit product and may cause harm.

Why was Reductil withdrawn?

Ongoing clinical studies have shown that Reductil tablets could have an adverse affect on the blood pressure and cardiovascular system of its patients. It was initially found that the medication was not deemed to pose a significant risk to those whose cardiovascular health was normal, which is why it was originally prescribed as an approved treatment.

However, major concerns were raised after a six year study of over 10,000 patients showed that the medication did in fact significantly increase the risk of heart disease, to the extent that the risk outweighed the proven benefits of weight loss. The study was considered controversial because the medication was tested on people with pre-existing cardiovascular problems, who should not have been prescribed the medication at all. Also, the six year length of the study was considerably longer than the maximum one year that Reductil should be prescribed.

Despite this controversy, Reductil was withdrawn as a result of the study and then banned in January 2010.

Is there an alternative medication?

Yes. There is currently only one prescription-only medication available to treat obesity, and that is Xenical. Xenical is considered a very safe medication and is even approved for treatment in patients who are considered high-risk. While Reductil operated on the brain and nervous system, Xenical works on the digestive system. This means the risk of adverse side effects associated with Reductil are significantly reduced.

How does Xenical compare to Reductil?

Reductil Xenical
Active ingredient Sibutramine hydrochloride Orlistat (tetrahydrolipstatin)
Purpose An appetite suppressant that enhances the feeling of 'fullness' To prevent fat being absorbed into the body
How it works Affects the brain and nervous system. Affects the digestive system.
Increases the levels of noradrenalin and serotonin in the brain by blocking the nerve cells that release them, leading to a feeling of fullness, even if less food is eaten. Prevents fat being broken down by enzymes and absorbed by the digestive system. One third of fat per meal is blocked and passed through the body.
Success rates 77% of patients using the medication alongside a reduced-calorie diet and physical exercise lost a significant amount of weight. Proven to be effective in approximately 70% of users. Clinical trials have shown that patients can achieve a weight loss of 10% or more of their body weight in just one year.
Risks and side effects

The list of those at risk from Reductil is extensive and listed below.

Noted side effects include headaches, increased blood pressure, dry mouth and hot flushes, amongst others.

p>Low chance of risks.

Side effects are usually mild and are associated with the unabsorbed fat, which can lead to oily stools, flatulence and an increase in the number of bowel movements.

Dosage Available as Reductil 10mg and Reductil 15mg, taken once a day. One 120mg capsule taken three times a day.

Who is at risk with Reductil?

There are many risk groups not advised to take Reductil. These include:

  • Those under the age of 18 or over the age of 65
  • Pregnant or breastfeeding women
  • Those with a history of
    • Blocked arteries
    • Coronary artery disease
    • Drug, alcohol or medication dependence
    • Heart failure, tachycardia or arrhythmias
    • Strokes
    • Anorexia nervosa or bulimia nervosa
  • Those suffering from
    • Hyperthyroidism
    • Psychiatric disorders
    • Decreased liver or kidney function

Xenical is considered a safe treatment for most people who would have been considered ‘high risk’ under Reductil. To find out if Xenical is the best alternative for you, you can find additional information and buy Xenical here.

Like the majority of people who used Reductil, I was disappointed (to say the least) when they took Reductil off the market. I think secretly I’d always hoped that it would come back. However, a couple of months ago, due to my dangerously high cholesterol, and ‘orders’ from my doctor, I had to do something. So I started using Xenical, it was a rocky start and I had a few uncomfortable side effects, but once I learnt how to control what I ate, it went loads better. I’ve been on it for two months and I’ve managed to lose 6lbs, and I’m still going strong.

I’ve been using Xenical since the start of the year, and so far so good. Two years ago I used Reductil for a bit, but never again! To be fair, it worked like a charm, but I felt miserable and I was a nervous wreck the whole time I was on it.